OSC Colloquium: Juergen Czarske, Title: “Minimally invasive lens less multicore fiber endoscopy using 3D-printed holograms and deep learning for biomedicine”

Title: “Minimally invasive lens less multicore fiber endoscopy using 3D-printed holograms and deep learning for biomedicine” 

Abstract: 

Light has the potential to recognize the origins of diseases, enabling to prevent them, or to cure them early and gently. The early diagnosis is the key to improve the survival rate and cure rate of patients. However, conventional biopsy often takes several hours to a few days for the surgeon to know the results of the diagnosis. Optical histopathology offers real-time intraoperative diagnosis without tissue removal. Novel optical engineering approaches for minimally invasive fiber endoscopy using fluorescence light are presented. 

The paradigm-shift of lens less multicore fiber endoscopy is based on deep neural networks and wavefront shaping with femtosecond laser-based 3D printed holograms. The well-trained resolution enhancement network helps improving tumor recognition rate. It is promising for minimally invasive intraoperative diagnostics of cancer in neurosurgery. 

Bio: 

Juergen W Czarske 

Director, Chair Professor and Senator 

Excellence University TU Dresden 

Juergen W Czarske (Fellow EOS, OPTICA, SPIE, IET, IOP, Senior Member IEEE) is director, chair professor and senator of the Excellence University TU Dresden, Germany. He is director of Competence Center Biomedical Computational Laser Systems (BIOLAS) and advisor of SPIE-OPTICA-Student Chapter Dresden. Juergen is an international prize-winning inventor of laser-based technologies. His awards include the 2008 Berthold Leibinger Innovation Prize of Trumpf Laser, 2019 OPTICA, Joseph-Fraunhofer-Award/Robert-M.-Burley-Prize, 2020 Laser Instrumentation Award of IEEE Photonics Society, 2020 and 2021 SPIE Community Champion for volunteer activities, and 2022 SPIE Chandra S Vikram Award. Juergen has conducted more than 800 talks and papers, including more than 250 papers in peer-reviewed journals, over 150 invited talks and over 30 patents. He is Vice President of International Commission for Optics, ICO, and was the general chair of the world congress ICO-25-OWLS-16-Dresden-Germany-2022 with 3 Nobel laureates and participants from over 55 countries of 5A (Africa, America, Asia, Australia, and Amazing Europe).