High-Speed Lens-Free Holographics Sensing of Protein Molecules Using Quantitative Agglutination Assays

Date Published: August 17, 2021

The fabrication of three-dimensional (3D) microscale structures is critical for many applications, including strong and lightweight material development, medical device fabrication, microrobotics, and photonic applications. While 3D microfabrication has seen progress over the past decades, complex multicomponent integration with small or hierarchical feature sizes is still a challenge. Dr. Jeffrey Melzer and Dr. Euan McLeod have precisely fabricated 3D microstructures from two types of micron-scale building blocks linked by biochemical interactions using an optical positioning and linking (OPAL) platform based on optical tweezers technology. It is anticipated that OPAL will enable the assembly, augmentation, and repair of microstructures composed of specialty micro/nanomaterial building blocks to be used in new photonic, microfluidic, and biomedical devices. Read the published article.

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A look at the setup of the new QLAB sensor demonstrating its ability to detect Brownian motion in a liquid sample without blur.